Condoms & Lube ACT Can Condoms Cause Infections? Understanding the Link Happy V Can Condoms Cause UTIs? Understanding the Hidden Link Between Protection and Discomfort nixit Correct and consistent use of a female or male condom means you can enjoy sex while Preventing unintended pregnancy Preventing HIV and other sexually transmitted infections How to Detect Tampered Drug Tests Today's Clinical Lab Condoms protect against unplanned pregnancy and most sexually transmitted infections, including HIV, gonorrhoea, chlamydia, and syphilis. Use only water or silicone based lubricant with a condom during vaginal and particularly anal sex.