How Many Puffs of Vape Equal a Cigarette? NHS gives definitive answer on how many cigarettes one disposable vape is equivalent to Vapes may seem harmless but can actually expose the body to the same level of nicotine as multiple packs of cigarettes, increasing the risk of dependence without people realizing it. Free resources: 5 x V2 Cigs Prefilled Cartridges for E Cigarettes V2 Cigs UK Guide to E Cigarettes: Vaping vs. Smoking, How to Choose, Tips The nicotine content of many 2ml nicotine pods for multi pod devices is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. And if you are smoking