Pigmented lesions of the oral mucosa and perioral tissues: a flow chart for the diagnosis and some recommendations for the management Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics Lip melanotic macula Hoogstra Medical Centers Oral Melanotic Macule: Symptoms and Treatment Skinsight PT 141 Peptide Injections for ED Gameday Men's Health This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips. What Is PT 141? Mechanism, Benefits, and How It Works